ATP Fuel™ - NEW
Optimized Energy for Serious Mitochondrial Needs
ATP Fuel™ is designed to support the Krebs Cycle of cellular energy production. The Krebs Cycle takes place inside the mitochondria or “power plant” of the cell and it is the body’s primary energy producer.
ATP Fuel™ offers the top three energy nutrients and cofactors synergistically combined for maximum mitochondrial performance and energy production:
NT Factor Energy™
NADH
CoQ10
ATP Fuel™ starts with the base of our highly acclaimed NT Factor Energy™, and adds the two other well-researched energy producing nutrients, NADH and CoQ10 into one convenient and power-producing formula. Plus ATP Fuel™ is available in capsules.
NT Factor Energy™- to repair mitochondrial membranes NT Factor Energy™ was developed as a phospholipid delivery system to repair mitochondrial membranes that have been compromised due to acute and/or long-term health challenges.
Mitochondrial membranes contain their own DNA. If these membranes are damaged and not able to self-repair, they rely on healthy cells to donate their phospholipids. However, if there is a cascading impact of damaged cells splitting, the end result is a less than optimal energy level.
The product's efficacy is based on our proprietary method of extracting and stabilizing the phospholipids, and delivering them intact in the lower intestine for proper absorption. Phospholipids are very unstable and often oxidize in the manufacturing process or in the digestive tract before they can be presented for absorption in the lower intestine. After we stabilize the phospholipids, we wrap them in probiotics and prebiotics. Next, we add minerals and other nutrients to assist in the Krebs Energy Cycle and absorption. When the capsule reaches the lower intestine, the pre and probiotics are released first to promote a healthy flora. We follow this with the release of the NT Factor portion, whose matrix very closely matches that of the gastro intestinal mucosa. As these phospholipids are transported from cell to cell, they are absorbed into the outer and inner mitochondrial membranes --- allowing the mitochondria to provide its natural and healthy level of energy.
A healthy mitochondrial membrane:
allows more nutrients into the mitochondria to support the Krebs Cycle of energy production
is essential for the electron transport chain to efficiently produce healthy levels of ATP
promotes healthier (reduced) level of oxidative stress
NADH - to convert food into energy
NADH is the reduced (electron- energy rich) coenzyme form of vitamin B3 or B-Nicotinamide Adenine Dinucleotide. This "reducing" power (its ability to donate electrons) is what drives ATP production.
NADH is fundamental in the chemical process of converting the food we eat into cellular energy. Each unit of NADH creates three units of ATP (the body's energy fuel).
Studies conducted in Europe indicated that NADH promotes healthy energy levels and emotional balance.
NADH is notoriously unstable. As part of our proprietary formula, we stabilize our NADH with chlorophyll, followed by microencapsulation process to resist gastric acids.
Coenzyme Q10 - for ATP energy production
Coenzyme Q10 (CoQ10) is a compound found naturally in the energy-producing center of the cell known as the mitochondria. CoQ10 is involved in the making of ATP. ATP serves as the cell's major energy source and drives a number of biological processes including muscle contraction and the production of protein. CoQ10 also works as an antioxidant.
CoQ10 promotes healthy energy levels, enhances the immune system, and acts as an antioxidant. A growing body of research suggests that using coenzyme Q10 supplements alone or in combination with other drug therapies and nutritional supplements supports the body’s health in promoting a healthy heart, promoting healthy periodontal (gum) condition, and in supporting cognitive and nerve health.*
Mitochondria - what are they & why are they so important? Mitochondria are the primary energy producers in the body. The typical cell contains an average of 1,000 mitochondria. Given that there are 10 to the 13th power cells in a healthy adult, healthy and productive mitochondria are critical to maintain the body's energy and resilience.
Recent studies have shown the importance to maintaining healthy MTDNA, the DNA which resides inside the mitochondria. Unlike standard DNA which has histones and introns to protect it from free radical damage, the mitochondrial DNA does not have this protective mechanism so it is much more exposed and more susceptible to oxidative damage (ROS or reactive oxidative stress). And since mitochondrial cell division takes place approximately every five to six days and replicates the damage existing in the old cells, the damaged MTDNA spreads rapidly. This is what eventually depletes the patient's energy level and may lead to abnormal cellular formation.
Showing posts with label chronic fatigue syndrome. Show all posts
Showing posts with label chronic fatigue syndrome. Show all posts
Wednesday, October 26, 2011
Thursday, May 5, 2011
Energy Multi-Plex - Adrenal Support Formula
Adrenal Support Formula with 14 researched nutrients
Our product developers were assigned the task of developing the most advanced adrenal support product based on published research. After a thorough review of the literature, they formulated Energy Multi-Plex™ --- the total energy formula. A favorite among doctors and patients, Energy Multi-Plex™ is a reasonably priced answer to many people's dreams of more energy.
“I have improved energy after supplementing with NT Factor Energy and Energy Multi-Plex. Especially notable are the increased maximal sudden power, endurance, and ability to recover during exercise and also for the next day events - for example in distance bicycling on hilly roads and weight lifting and aerobic exercising at the Y.
These two Researched Nutritionals products were added to a thorough treatment program for a longer-term fatigue illness from tick borne infection complex illness in the later, more recent stages of therapy. I think the products address some of what we know about mitochondrial damage in the longer-term fatigue- like syndromes and look forward to discussing this further with others interested in increased energy. I have no conflicts of interest in my dialogues regarding Researched Nutritionals products.” --- H. Smith MD
Each bottle provides a one month supply of the following complexes and health benefits:
Energymax™ Complex:
Targeted blend of D-ribose, panax ginseng which
• promotes healthy energy levels by raising the level of the body’s energy fuel, ATP
• supports healthy cognitive performance
MuscularEnergy™ Complex:
Combination of malic acid and rhodiola rosea which
• plays a key role in energy producing Kreb’s Cycle
• has an adaptogenic affect to support physical activity
Mitrochondria Energizer™ Complex:
Powerful duo of acetyl-L-carnitine and alpha lipoic acid which
• acts as a catalyst for ATP production in mitochondria
• improves mitochondrial function while promoting healthy cognitive function
Metabolism Plus™ Complex:
Natural, non-stimulation blend of pyruvic acid and 7-Keto DHEA which
• naturally increases, without artificial stimulation, resting metabolism
• multiple studies
show increased fat utilization (fat loss) as an energy source
• promotes fat loss through thermogenesis
HeartStrong™ Complex:
High potency Co Q10 and L-Taurine which
• is used by the body to transform food into adenosine triphosphate (ATP), the energy on which the body runs
• promotes healthy heart and gum tissue
• modulates the immune system
• promotes healthy heart beat and cell wall stability
Key Nutrient Blend:
pantothenic acid, vitamin B-12, magnesium and potassium which
• are essential nutrients involved in producing, transporting and releasing energy from fat
• promotes healthy neuromuscular function and muscle contractions
Suggested Use
As a dietary supplement, take three capsules per day (at one time or throughout the day) or as directed by your healthcare professional.
Our product developers were assigned the task of developing the most advanced adrenal support product based on published research. After a thorough review of the literature, they formulated Energy Multi-Plex™ --- the total energy formula. A favorite among doctors and patients, Energy Multi-Plex™ is a reasonably priced answer to many people's dreams of more energy.
“I have improved energy after supplementing with NT Factor Energy and Energy Multi-Plex. Especially notable are the increased maximal sudden power, endurance, and ability to recover during exercise and also for the next day events - for example in distance bicycling on hilly roads and weight lifting and aerobic exercising at the Y.
These two Researched Nutritionals products were added to a thorough treatment program for a longer-term fatigue illness from tick borne infection complex illness in the later, more recent stages of therapy. I think the products address some of what we know about mitochondrial damage in the longer-term fatigue- like syndromes and look forward to discussing this further with others interested in increased energy. I have no conflicts of interest in my dialogues regarding Researched Nutritionals products.” --- H. Smith MD
Each bottle provides a one month supply of the following complexes and health benefits:
Energymax™ Complex:
Targeted blend of D-ribose, panax ginseng which
• promotes healthy energy levels by raising the level of the body’s energy fuel, ATP
• supports healthy cognitive performance
MuscularEnergy™ Complex:
Combination of malic acid and rhodiola rosea which
• plays a key role in energy producing Kreb’s Cycle
• has an adaptogenic affect to support physical activity
Mitrochondria Energizer™ Complex:
Powerful duo of acetyl-L-carnitine and alpha lipoic acid which
• acts as a catalyst for ATP production in mitochondria
• improves mitochondrial function while promoting healthy cognitive function
Metabolism Plus™ Complex:
Natural, non-stimulation blend of pyruvic acid and 7-Keto DHEA which
• naturally increases, without artificial stimulation, resting metabolism
• multiple studies
show increased fat utilization (fat loss) as an energy source
• promotes fat loss through thermogenesis
HeartStrong™ Complex:
High potency Co Q10 and L-Taurine which
• is used by the body to transform food into adenosine triphosphate (ATP), the energy on which the body runs
• promotes healthy heart and gum tissue
• modulates the immune system
• promotes healthy heart beat and cell wall stability
Key Nutrient Blend:
pantothenic acid, vitamin B-12, magnesium and potassium which
• are essential nutrients involved in producing, transporting and releasing energy from fat
• promotes healthy neuromuscular function and muscle contractions
Suggested Use
As a dietary supplement, take three capsules per day (at one time or throughout the day) or as directed by your healthcare professional.
Tuesday, June 22, 2010
Relief from Fatigue
Buy Corvalen Ribose at best lowest price FREE shipping.
Corvalen is a non-prescription medical food that specifically addresses a nutritional deficiency associated with particular diseases that result in fatigue and pain. Using GRAS-approved Corvalen, with the active ingredient ribose, patients can overcome this fatigue and pain more quickly.
Corvalen aids patients suffering from compromised heart function, Fibromyalgia (FMS) and Chronic Fatigue Syndrome (CFS) by restoring depleted energy reserves at a cellular level. Clinically-proven studies have shown a reduction of fatigue, muscle soreness, stiffness and pain with patients that use Corvalen.
Scientific and clinical studies have repeatedly shown that Corvalen, with the active ingredient ribose, can restore energy and improve function in ischemic, hypoxic, and failing hearts. Oxygen deprivation causes hearts to use energy faster than it can be replaced through normal processes of tissue energy turnover. The result is a depletion of cellular energy reserves translating to loss of heart function.
Millions of Americans suffer the affects of coronary artery disease, and the prevalence of congestive heart failure is reaching epidemic proportions. Recent research has also proven that high-intensity endurance exercise places a considerable strain on the heart, leading to a loss of diastolic heart function that persists for several weeks to months following an event. Other research, conducted at the Mayo Clinic and published in the Journal of the American Medical Association, showed that an average of 26% of the population, male and female, have symptoms of cardiac diastolic dysfunction. More than half of those affected are unaware of their condition, but all are at risk for developing congestive heart failure.
When hearts lose energy, they first suffer a loss of diastolic function. The diastolic phase of the heartbeat is the relaxation phase, during which the heart fills with blood for the next heartbeat. A loss of diastolic capacity means less blood will circulate to the body during each beat, and frequently leads to a thickening and expansion of the heart muscle, known as hypertrophy. The result of chronic diastolic dysfunction can be congestive heart failure. For patients, the progressive consequence of the disease is shortness of breath, loss of exercise capacity, overwhelming fatigue, etc.
Corvalen increases cardiac energy to help fuel the heart. For patients, this can mean more energy and a higher quality of life. For athletes, it can enhance recovery following strenuous exercise.
Corvalen is a non-prescription medical food that specifically addresses a nutritional deficiency associated with particular diseases that result in fatigue and pain. Using GRAS-approved Corvalen, with the active ingredient ribose, patients can overcome this fatigue and pain more quickly.
Corvalen aids patients suffering from compromised heart function, Fibromyalgia (FMS) and Chronic Fatigue Syndrome (CFS) by restoring depleted energy reserves at a cellular level. Clinically-proven studies have shown a reduction of fatigue, muscle soreness, stiffness and pain with patients that use Corvalen.
Scientific and clinical studies have repeatedly shown that Corvalen, with the active ingredient ribose, can restore energy and improve function in ischemic, hypoxic, and failing hearts. Oxygen deprivation causes hearts to use energy faster than it can be replaced through normal processes of tissue energy turnover. The result is a depletion of cellular energy reserves translating to loss of heart function.
Millions of Americans suffer the affects of coronary artery disease, and the prevalence of congestive heart failure is reaching epidemic proportions. Recent research has also proven that high-intensity endurance exercise places a considerable strain on the heart, leading to a loss of diastolic heart function that persists for several weeks to months following an event. Other research, conducted at the Mayo Clinic and published in the Journal of the American Medical Association, showed that an average of 26% of the population, male and female, have symptoms of cardiac diastolic dysfunction. More than half of those affected are unaware of their condition, but all are at risk for developing congestive heart failure.
When hearts lose energy, they first suffer a loss of diastolic function. The diastolic phase of the heartbeat is the relaxation phase, during which the heart fills with blood for the next heartbeat. A loss of diastolic capacity means less blood will circulate to the body during each beat, and frequently leads to a thickening and expansion of the heart muscle, known as hypertrophy. The result of chronic diastolic dysfunction can be congestive heart failure. For patients, the progressive consequence of the disease is shortness of breath, loss of exercise capacity, overwhelming fatigue, etc.
Corvalen increases cardiac energy to help fuel the heart. For patients, this can mean more energy and a higher quality of life. For athletes, it can enhance recovery following strenuous exercise.
Corvalen Ribose - How it Works
Buy Corvalen Ribose at the best lowest price with free shipping.
Corvalen energy supplement and clinical nutrition products contain D-ribose (or simply ribose). Ribose is vital for your body to make the primary energy compound, adenosine triphosphate (ATP). ATP gives your body the energy it needs to stay healthy, overcome fatigue, and regain the vitality you need to live a normal, active life. That is why ATP is called the "energy currency" of the cell.
D-ribose, or simply ribose, is a five-carbon monosaccharide that is made in every cell in your body. Ribose stimulates the metabolic pathway used by the body to make a class of compounds called purines and pyrimidines. These compounds are essential for the body's production of many vital constituents, including the genetic material DNA and RNA, and the vital energy compound ATP.
The ribose in Corvalen helps energize your heart and muscles by increasing energy on a cellular level. Aging, strenuous exercise or overexertion, and many metabolic or physiological conditions can drain ATP from your tissue and affect how well your body makes and uses energy. Science has proven that ribose is a necessary ingredient for rebuilding energy in our bodies. So, without ribose we cannot make the energy we need to stay healthy.
Unfortunately, hearts, muscles, and other vital tissues in the body cannot make ribose very quickly, and ribose is not stored in our cells and tissues. That's why supplementing with Corvalen as directed will help your cells make energy quickly, safely, and naturally. This means you can feel more energetic, stronger, and healthier every day.
Corvalen energy supplement and clinical nutrition products contain D-ribose (or simply ribose). Ribose is vital for your body to make the primary energy compound, adenosine triphosphate (ATP). ATP gives your body the energy it needs to stay healthy, overcome fatigue, and regain the vitality you need to live a normal, active life. That is why ATP is called the "energy currency" of the cell.
D-ribose, or simply ribose, is a five-carbon monosaccharide that is made in every cell in your body. Ribose stimulates the metabolic pathway used by the body to make a class of compounds called purines and pyrimidines. These compounds are essential for the body's production of many vital constituents, including the genetic material DNA and RNA, and the vital energy compound ATP.
The ribose in Corvalen helps energize your heart and muscles by increasing energy on a cellular level. Aging, strenuous exercise or overexertion, and many metabolic or physiological conditions can drain ATP from your tissue and affect how well your body makes and uses energy. Science has proven that ribose is a necessary ingredient for rebuilding energy in our bodies. So, without ribose we cannot make the energy we need to stay healthy.
Unfortunately, hearts, muscles, and other vital tissues in the body cannot make ribose very quickly, and ribose is not stored in our cells and tissues. That's why supplementing with Corvalen as directed will help your cells make energy quickly, safely, and naturally. This means you can feel more energetic, stronger, and healthier every day.
Monday, March 9, 2009
What is the difference between CORvalen and CorvalenM?
What is the difference between CORvalen and CorvalenM? Both products recommend 5 grams per serving, and both have the same number of servings of D-ribose the principal active ingredient. In addition, CorvalenM contains magnesium and malate, both shown to improve muscle metabolism and relaxation.
How do I know which is best for me? As a general rule, CORvalen is recommended for heart patients and athletic applications. CorvalenM is used more for muscle aches, pain, soreness, and stiffness. But there are many exceptions with each. Ask yourself, Does my diet need additional magnesium? Magnesium is important for over 200 chemical reactions in the body. Some say the American diet contains less and less natural magnesium because more of our food is processed and we drink more bottled water and beverages than a couple of generations ago.
Conversely, too much magnesium leads to loose stools and diarrhea. You can pick up magnesium from several sources vitamin pills and other supplements.
What are the ingredients for each product? CORvalen is 100% D-ribose. Each serving contains 5g of D-ribose. CORvalen M contains D-ribose, malate and magnesium. For each serving of CORvalen M, there is 5g D-ribose, 240mg Malate (or malic acid) and 800mg magnesium gluconate (the same as 40mg elemental magnesium). CORvalen Chewable Wafers each contain 1.67 grams D-ribose. Other ingredients include inulin, cocoa bean powder, mannitol, modified cellulose, safflower oil, coconut powder, stearic acid, silicon dioxide and natural flavors.
What is ribose? D-Ribose is a simple, 5-carbon monosaccharide, or pentose sugar. It is used by all the cells of the body and is an essential compound in energy metabolism. Ribose is also the carbohydrate backbone of genetic material, DNA and RNA, certain vitamins and other important cellular compounds.
Who needs CORvalen? Ribose is an essential ingredient in stimulating natural energy production. Research has shown that ribose promotes cardiovascular health, reduces cardiac stress associated with strenuous activity and helps athletes extend their exercise tolerance and accelerates recovery. Ribose helps hearts and muscles maximize energy recovery. Whether you are a trained athlete, a weekend warrior or are concerned about your cardiovascular health, ribose may help give the energy boost your body needs.
How is ribose made in the body? Most compounds necessary for life are made in the body through a series of complicated pathways. Ribose is no different. In the body, ribose is made from glucose (a simple 6-carbon sugar) through a pathway called the Pentose Phosphate Pathway (PPP). Eventually, adenosine triphosphate (ATP) is produced. ATP is the primary energy molecule in your body’s cells. Though your body makes ribose and ATP naturally, it produces it slowly. As a result, your heart and muscle tissues use their energy faster than they can restore it and the energy pools become depleted.
How does the body derive cellular energy from ribose? The physiologically functional form of ribose, called 5-phosphoribosyl-1-pyrophosphate (PRPP), regulates the metabolic pathway that synthesizes energy compounds in all living tissue. If this compound is not available in sufficient quantity, energy synthesis slows.
How does taking supplemental CORvalen aid in increasing cellular energy? If the cellular energy pool is depleted by disease or exercise, it must be replaced. PRPP is required to turn on the metabolic pathway used by the body to replenish these energy pools. Supplemental ribose bypasses the slow and rate-limiting enzymes in the Pentose Phosphate Pathway, forms PRPP, and quickly begins the process of energy synthesis.
What will CORvalen do for someone concerned about cardiovascular health? Numerous medical studies have shown that energy levels in the heart can be dramatically lowered by exercise or decreased blood flow associated with certain cardiac diseases. Depleted cardiac energy pools may be associated with increased cardiac stress, altered cardiac function, fatigue and decreased exercise tolerance. Ribose is the key nutrient for quickly restoring cardiac energy stores.
What is the recommended daily dosage of CORvalen? Usual dosage: 5g serving twice daily, taken with meals. A third serving may be added with a midday meal as needed.
Alternative dosage: 5g just before and just after exercise or physical activity.
Serving measurement: 5g of CORvalen powder is a rounded teaspoonful. A single dose measuring scoop is provided with each jar.
CORvalen may be dissolved in 2 oz. or more of juice, tea, or coffee or sprinkled over foods of choice (such as hot oatmeal, yogurt, cold cereal). CorvalenM has a more citrus flavor so it is best in juice, water or yogurt. CORvalen and CorvalenM should NOT be mixed into carbonated beverages.
To maximize athletic performance, or to keep energy pools high during strenuous activity, slightly larger doses may be required. CORvalen (D-ribose) should be taken just before and just after exercise or activity. For extended exercise, an additional 1 to 2 grams per hour of exercise or activity may be helpful.
When can I expect to feel results/benefits from taking CORvalen? Individual response varies widely, but relief from fatigue is often felt within the first 10 days of consistent use.
What can I mix with CORvalen? CORvalen may be mixed with water, juice, coffee, tea or sprinkled on cereal or fruit. It has a mild pleasant sweet taste and is very flexible.
Are there any side effects associated with taking ribose? CORvalen may lower blood sugar for 60 to 90 minutes after ingestion. This may cause one to feel very hungry or lightheaded. This can be avoided by taking with meals or with some form of a carbohydrate such as a juice.
What will ribose do for someone who exercises on a regular basis? Scientific research shows that three or four workouts per week may not allow enough rest time between sessions for heart and muscle energy pools to return to normal levels. Taking CORvalen (D-ribose) shortens the time needed by heart and muscle tissue to replace energy that is lost through vigorous exercise. Keeping energy pools full helps to keep hearts and muscles in good physiological condition, increase power and endurance, and reduce fatigue. Recent research has also shown that ribose supplementation during exercise manages free radical formation and lowers cardiac stress associated with hypoxia.
Does CORvalen conflict with any medications? There are no known interactions with drugs or other supplements.
Does ribose work with creatine or other supplements? Ribose can increase the effect of creatine and other energy supplements by keeping the energy pool at full capacity. Creatine works by recycling energy that is already present in the tissue. Another supplement, carnitine, aids in fatty acid metabolism. A third, pyruvate, also helps to recycle energy. Only ribose performs this important metabolic function. Without adequate levels of energy to work with, no other supplement can be fully effective.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
How do I know which is best for me? As a general rule, CORvalen is recommended for heart patients and athletic applications. CorvalenM is used more for muscle aches, pain, soreness, and stiffness. But there are many exceptions with each. Ask yourself, Does my diet need additional magnesium? Magnesium is important for over 200 chemical reactions in the body. Some say the American diet contains less and less natural magnesium because more of our food is processed and we drink more bottled water and beverages than a couple of generations ago.
Conversely, too much magnesium leads to loose stools and diarrhea. You can pick up magnesium from several sources vitamin pills and other supplements.
What are the ingredients for each product? CORvalen is 100% D-ribose. Each serving contains 5g of D-ribose. CORvalen M contains D-ribose, malate and magnesium. For each serving of CORvalen M, there is 5g D-ribose, 240mg Malate (or malic acid) and 800mg magnesium gluconate (the same as 40mg elemental magnesium). CORvalen Chewable Wafers each contain 1.67 grams D-ribose. Other ingredients include inulin, cocoa bean powder, mannitol, modified cellulose, safflower oil, coconut powder, stearic acid, silicon dioxide and natural flavors.
What is ribose? D-Ribose is a simple, 5-carbon monosaccharide, or pentose sugar. It is used by all the cells of the body and is an essential compound in energy metabolism. Ribose is also the carbohydrate backbone of genetic material, DNA and RNA, certain vitamins and other important cellular compounds.
Who needs CORvalen? Ribose is an essential ingredient in stimulating natural energy production. Research has shown that ribose promotes cardiovascular health, reduces cardiac stress associated with strenuous activity and helps athletes extend their exercise tolerance and accelerates recovery. Ribose helps hearts and muscles maximize energy recovery. Whether you are a trained athlete, a weekend warrior or are concerned about your cardiovascular health, ribose may help give the energy boost your body needs.
How is ribose made in the body? Most compounds necessary for life are made in the body through a series of complicated pathways. Ribose is no different. In the body, ribose is made from glucose (a simple 6-carbon sugar) through a pathway called the Pentose Phosphate Pathway (PPP). Eventually, adenosine triphosphate (ATP) is produced. ATP is the primary energy molecule in your body’s cells. Though your body makes ribose and ATP naturally, it produces it slowly. As a result, your heart and muscle tissues use their energy faster than they can restore it and the energy pools become depleted.
How does the body derive cellular energy from ribose? The physiologically functional form of ribose, called 5-phosphoribosyl-1-pyrophosphate (PRPP), regulates the metabolic pathway that synthesizes energy compounds in all living tissue. If this compound is not available in sufficient quantity, energy synthesis slows.
How does taking supplemental CORvalen aid in increasing cellular energy? If the cellular energy pool is depleted by disease or exercise, it must be replaced. PRPP is required to turn on the metabolic pathway used by the body to replenish these energy pools. Supplemental ribose bypasses the slow and rate-limiting enzymes in the Pentose Phosphate Pathway, forms PRPP, and quickly begins the process of energy synthesis.
What will CORvalen do for someone concerned about cardiovascular health? Numerous medical studies have shown that energy levels in the heart can be dramatically lowered by exercise or decreased blood flow associated with certain cardiac diseases. Depleted cardiac energy pools may be associated with increased cardiac stress, altered cardiac function, fatigue and decreased exercise tolerance. Ribose is the key nutrient for quickly restoring cardiac energy stores.
What is the recommended daily dosage of CORvalen? Usual dosage: 5g serving twice daily, taken with meals. A third serving may be added with a midday meal as needed.
Alternative dosage: 5g just before and just after exercise or physical activity.
Serving measurement: 5g of CORvalen powder is a rounded teaspoonful. A single dose measuring scoop is provided with each jar.
CORvalen may be dissolved in 2 oz. or more of juice, tea, or coffee or sprinkled over foods of choice (such as hot oatmeal, yogurt, cold cereal). CorvalenM has a more citrus flavor so it is best in juice, water or yogurt. CORvalen and CorvalenM should NOT be mixed into carbonated beverages.
To maximize athletic performance, or to keep energy pools high during strenuous activity, slightly larger doses may be required. CORvalen (D-ribose) should be taken just before and just after exercise or activity. For extended exercise, an additional 1 to 2 grams per hour of exercise or activity may be helpful.
When can I expect to feel results/benefits from taking CORvalen? Individual response varies widely, but relief from fatigue is often felt within the first 10 days of consistent use.
What can I mix with CORvalen? CORvalen may be mixed with water, juice, coffee, tea or sprinkled on cereal or fruit. It has a mild pleasant sweet taste and is very flexible.
Are there any side effects associated with taking ribose? CORvalen may lower blood sugar for 60 to 90 minutes after ingestion. This may cause one to feel very hungry or lightheaded. This can be avoided by taking with meals or with some form of a carbohydrate such as a juice.
What will ribose do for someone who exercises on a regular basis? Scientific research shows that three or four workouts per week may not allow enough rest time between sessions for heart and muscle energy pools to return to normal levels. Taking CORvalen (D-ribose) shortens the time needed by heart and muscle tissue to replace energy that is lost through vigorous exercise. Keeping energy pools full helps to keep hearts and muscles in good physiological condition, increase power and endurance, and reduce fatigue. Recent research has also shown that ribose supplementation during exercise manages free radical formation and lowers cardiac stress associated with hypoxia.
Does CORvalen conflict with any medications? There are no known interactions with drugs or other supplements.
Does ribose work with creatine or other supplements? Ribose can increase the effect of creatine and other energy supplements by keeping the energy pool at full capacity. Creatine works by recycling energy that is already present in the tissue. Another supplement, carnitine, aids in fatty acid metabolism. A third, pyruvate, also helps to recycle energy. Only ribose performs this important metabolic function. Without adequate levels of energy to work with, no other supplement can be fully effective.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Saturday, December 6, 2008
NUTRITIONAL SUPPORT IN A PATIENT WITH CHRONIC FATIGUE SYNDROME
NUTRITIONAL SUPPORT USING ULTRACLEAR PLUS ® AND ULTRACLEAR SUSTAIN®
IN A PATIENT WITH CHRONIC FATIGUE SYNDROME
Purpose: To show how a targeted nutritional support program featuring UltraClear PLUS medical food for detoxification and UltraClear SUSTAIN medical food for gastrointestinal (GI)
support may be useful in some patients with long-standing chronic fatigue syndrome (CFS).
Patient’s Presentation and History: A 42-year-old Caucasian female presented with CFS,
reporting unremitting fatigue, insomnia, chronic arthralgias and myalgias, post-exertion exhaustion, cognitive dysfunction, cyclical acne, recurrent sinus and strep infections, and
increasing sensitivity to environmental stimuli (e.g., tobacco smoke, perfumes, newsprint). At the time of presentation, she was on disability and unable to work. The patient primarily ate
organic foods, and noted some bloating with wheat and dairy. She had a history of hypothyroidism, mononucleosis, allergies, migraines, 6 weeks of “colitis -like” symptoms after
pesticide exposure, and multiple antibiotic courses.
Patient’s Objective Information
· BMI†: 22.8; BP: 120/80
· MSQ* score 129
· Results of HEENT exam: notable allergic shiners, lungs lear to auscultation
· Thyroid palpable, liver non-tender, abdomen soft with diffuse tenderness in right and left upper quadrants
· Along with dry skin, reddened vesicles in various stages of eruption, healing, and scarring noted on anterior arms, forearms, calves, and thighs
· Prescriptive medications and supplements included spironolactone (75 mg/day), desiccated thyroid (120 mg/day), and a variety of nutritional supplements
· Assessment: CFS, multiple chemical sensitivities, possible food allergies, and adrenal fatigue
Plan: In addition to continuing prescriptive medications and discontinuing supplements, the patient was instructed to begin taking:
· UltraClear PLUS medical food, 3 servings daily
· Licorice root extract, ¼ tsp qd
· Extract of 7 mushrooms, 30 drops bid
· Multivitamin/mineral supplement without iron, 2 tablets bid
1 and 3 Week Results
The patient’s laboratory results from week 1 showed altered intestinal permeability and detoxification. After 3 weeks on the program, the patient reported improvements in sleep, cognition, and energy and was instructed to:
· Continue UltraClear PLUS, licorice root, multivitamin/mineral supplement without iron
· Discontinue mushroom extract
· Add elimination diet, fiber supplement (1 scoop tid), glutamine (5 grams tid)
8 and 12 Week Results
The patient’s fatigue, energy, and sleep continued to improve. Prior to the program, she was sleeping 14-16 hr/day, decreasing to 8-10 hr/day after 8 weeks on the program. She was instructed to continue the protocol and add sodium sulfate (20 mg bid) to help manage chemical sensitivities. The patient indicated a 30% to 40% improvement overall after 12 weeks, and said she was better able to withstand chemical exposures. Intestinal permeability and detoxification laboratory values also improved. The patient was instructed to add a supplement to support mitochondrial energy production (2 capsules tid).
20 and 32 Week Results
The patient continued to do well and rated her overall improvement at 50% by the 20th week. She was instructed to:
· Continue the elimination diet, licorice root extract, multivitamin/mineral supplement, and fiber supplement
· Discontinue UltraClear PLUS, mitochondrial support supplement, and glutamine
· Begin taking UltraClear SUSTAIN medical food, 2 scoops bid
· Increase sodium sulfate, 400 mg bid
· Add N-acetylcysteine, 500 mg tid
After 32 weeks, the patient was no longer bedridden and continued to show improvement. She decided to remove mercury amalgams and had two chelation IV therapies. The patient noted that support for detoxification, particularly the sodium sulfate, helped her manage chemical sensitivities.
Conclusion
This case study suggests that a focused nutritional program featuring UltraClear PLUS for detoxification and UltraClear SUSTAIN to support healthy GI function may help address
CFS symptoms—including multiple chemical sensitivities associated with long-term CFS.
CASE STUDY #909
Figure 1
After 32 weeks, the patient’s Medical Symptoms Questionnaire* score decreased from 129 to 18 (reference range: <30>RESULTS
strong86% Improvement in MSQ Score
129
18
0
50
100
150
Before Program After 32 Weeks
MSQ Score 91% Reduction in Intestinal Permeability ("Leaky Gut")
0.338
0.031
0
0.1
0.2
0.3
0.4
Initial Lab Results After 32 Weeks
Lactulose-Mannitol Ratio
2X the Total
Acetaminophen Recovery
40.60%
83.20%
0.00%
20.00%
40.00%
60.00%
80.00%
100.00%
Initial Lab Results
After 32 Weeks
AIMS2: Physical Score
†BMI is the Body Mass Index and can be computed by the weight (kg) divided by the square of the height (m).
*The Medical Symptoms Questionnaire (MSQ) is a clinical tool for the evaluation of general physical symptoms. Total scores above 75 are generally associated with substantial symptomatology and disability; scores below 30 generally indicate few or low intensity symptoms.
© Metagenics, Inc. MET909 4/04
Note: The information provided in this case study describes the results of one patient under the care of a licensed healthcare practitioner and may not be a typical response. UltraClear PLUS medical food and UltraClear SUSTAIN medical food are to be used under the supervision of a physician or other licensed healthcare practitioner.
Case Study: Nutritional Support Using UltraClear PLUS and UltraClear SUSTAIN in a Patient with Chronic Fatigue Syndrome. Metagenics, Inc.; 016CFS1203.
IN A PATIENT WITH CHRONIC FATIGUE SYNDROME
Purpose: To show how a targeted nutritional support program featuring UltraClear PLUS medical food for detoxification and UltraClear SUSTAIN medical food for gastrointestinal (GI)
support may be useful in some patients with long-standing chronic fatigue syndrome (CFS).
Patient’s Presentation and History: A 42-year-old Caucasian female presented with CFS,
reporting unremitting fatigue, insomnia, chronic arthralgias and myalgias, post-exertion exhaustion, cognitive dysfunction, cyclical acne, recurrent sinus and strep infections, and
increasing sensitivity to environmental stimuli (e.g., tobacco smoke, perfumes, newsprint). At the time of presentation, she was on disability and unable to work. The patient primarily ate
organic foods, and noted some bloating with wheat and dairy. She had a history of hypothyroidism, mononucleosis, allergies, migraines, 6 weeks of “colitis -like” symptoms after
pesticide exposure, and multiple antibiotic courses.
Patient’s Objective Information
· BMI†: 22.8; BP: 120/80
· MSQ* score 129
· Results of HEENT exam: notable allergic shiners, lungs lear to auscultation
· Thyroid palpable, liver non-tender, abdomen soft with diffuse tenderness in right and left upper quadrants
· Along with dry skin, reddened vesicles in various stages of eruption, healing, and scarring noted on anterior arms, forearms, calves, and thighs
· Prescriptive medications and supplements included spironolactone (75 mg/day), desiccated thyroid (120 mg/day), and a variety of nutritional supplements
· Assessment: CFS, multiple chemical sensitivities, possible food allergies, and adrenal fatigue
Plan: In addition to continuing prescriptive medications and discontinuing supplements, the patient was instructed to begin taking:
· UltraClear PLUS medical food, 3 servings daily
· Licorice root extract, ¼ tsp qd
· Extract of 7 mushrooms, 30 drops bid
· Multivitamin/mineral supplement without iron, 2 tablets bid
1 and 3 Week Results
The patient’s laboratory results from week 1 showed altered intestinal permeability and detoxification. After 3 weeks on the program, the patient reported improvements in sleep, cognition, and energy and was instructed to:
· Continue UltraClear PLUS, licorice root, multivitamin/mineral supplement without iron
· Discontinue mushroom extract
· Add elimination diet, fiber supplement (1 scoop tid), glutamine (5 grams tid)
8 and 12 Week Results
The patient’s fatigue, energy, and sleep continued to improve. Prior to the program, she was sleeping 14-16 hr/day, decreasing to 8-10 hr/day after 8 weeks on the program. She was instructed to continue the protocol and add sodium sulfate (20 mg bid) to help manage chemical sensitivities. The patient indicated a 30% to 40% improvement overall after 12 weeks, and said she was better able to withstand chemical exposures. Intestinal permeability and detoxification laboratory values also improved. The patient was instructed to add a supplement to support mitochondrial energy production (2 capsules tid).
20 and 32 Week Results
The patient continued to do well and rated her overall improvement at 50% by the 20th week. She was instructed to:
· Continue the elimination diet, licorice root extract, multivitamin/mineral supplement, and fiber supplement
· Discontinue UltraClear PLUS, mitochondrial support supplement, and glutamine
· Begin taking UltraClear SUSTAIN medical food, 2 scoops bid
· Increase sodium sulfate, 400 mg bid
· Add N-acetylcysteine, 500 mg tid
After 32 weeks, the patient was no longer bedridden and continued to show improvement. She decided to remove mercury amalgams and had two chelation IV therapies. The patient noted that support for detoxification, particularly the sodium sulfate, helped her manage chemical sensitivities.
Conclusion
This case study suggests that a focused nutritional program featuring UltraClear PLUS for detoxification and UltraClear SUSTAIN to support healthy GI function may help address
CFS symptoms—including multiple chemical sensitivities associated with long-term CFS.
CASE STUDY #909
Figure 1
After 32 weeks, the patient’s Medical Symptoms Questionnaire* score decreased from 129 to 18 (reference range: <30>RESULTS
strong86% Improvement in MSQ Score
129
18
0
50
100
150
Before Program After 32 Weeks
MSQ Score 91% Reduction in Intestinal Permeability ("Leaky Gut")
0.338
0.031
0
0.1
0.2
0.3
0.4
Initial Lab Results After 32 Weeks
Lactulose-Mannitol Ratio
2X the Total
Acetaminophen Recovery
40.60%
83.20%
0.00%
20.00%
40.00%
60.00%
80.00%
100.00%
Initial Lab Results
After 32 Weeks
AIMS2: Physical Score
†BMI is the Body Mass Index and can be computed by the weight (kg) divided by the square of the height (m).
*The Medical Symptoms Questionnaire (MSQ) is a clinical tool for the evaluation of general physical symptoms. Total scores above 75 are generally associated with substantial symptomatology and disability; scores below 30 generally indicate few or low intensity symptoms.
© Metagenics, Inc. MET909 4/04
Note: The information provided in this case study describes the results of one patient under the care of a licensed healthcare practitioner and may not be a typical response. UltraClear PLUS medical food and UltraClear SUSTAIN medical food are to be used under the supervision of a physician or other licensed healthcare practitioner.
Case Study: Nutritional Support Using UltraClear PLUS and UltraClear SUSTAIN in a Patient with Chronic Fatigue Syndrome. Metagenics, Inc.; 016CFS1203.
Saturday, April 19, 2008
Fibromyalgia, Pain Relief & Energy with Malic Acid
Malic Acid, Energy, & Fibromyalgia
Improvement in pain observed within 48 hours of supplementation with 1200-2400 mg. of malic acid per day. Buy Metagenics Fibroplex with magnesium and malic acid at a discount
Combine Bioenergy Corvalen Ribose with Metagenics Fibroplex for muscle pains and energy - Corvalen Lowest Price with Free Shipping
Primary fibromyalgia (FM) is a condition affecting principally middle-aged women, characterized by a syndrome of generalized musculoskeletal pain, aches, stiffness, and tenderness at specific anatomical sites. This condition is considered primary when there are no obvious causes. Since it was first described, FM has become recognized as a fairly common rheumatic complaint with a clinical prevalence of 6 to 20 percent. Additionally, FM has been associated with irritable bowel syndrome, tension headache, mitral valve prolapse, and chronic fatigue syndrome. Numerous treatment modalities have been attempted to treat patients with FM, but unfortunately the results have usually been poor. The primary reason for this lack of success was undoubtedly due to our lack of understanding FMs etiology.
In recent years, evidence has accumulated to suggest that FM is the result of local hypoxia in the muscles. For instance, patients with FM have low muscle-tissue oxygen pressure in affected muscles, and to a lesser degree the same was found in other tissues. Muscle biopsies from affected areas showed muscle tissue breakdown and mitochondrial damage. Additionally, low levels of the high energy phosphates ATP, ADP, and phosphocreatine were found. It has been hypothesized that in hypoxic muscle tissues glycolysis is inhibited, reducing ATP synthesis. This stimulates the process of gluconeogenesis, which results in the breakdown of muscle proteins to amino acids that can be utilized as substrates for ATP synthesis. This muscle tissue breakdown, which has been observed in muscle biopsies taken from FM patients, is hypothesized to result in the muscle pain characteristic of FM.
Malic acid is both derived from food sources and synthesized in the body through the citric acid (Krebs) cycle. Its importance to the production of energy in the body during both aerobic and anaerobic conditions is well established. Under aerobic conditions, the oxidation of malate to oxaloacetate provides reducing equivalents to the mitochondria through the malate-aspartate redox shuttle. During anaerobic conditions, where a buildup of excess of reducing equivalents inhibits glycolysis, malic acids simultaneous reduction to succinate and oxidation to oxaloacetate is capable of removing the accumulating reducing equivalents. This allows malic acid to reverse hypoxias inhibition of glycolysis and energy production. This may allow malic acid to improve energy production in FM, reversing the negative effect of the relative hypoxia that has been found in these patients.
Because of its obvious relationship to energy depletion during exercise, malic acid may be of benefit to healthy individuals interested in maximizing their energy production, as well as those with FM. In the rat it has been found that only tissue malate is depleted following exhaustive physical activity. Other key metabolites from the citric acid cycle needed for energy production were found to be unchanged. Because of this, a deficiency of malic acid has been hypothesized to be a major cause of physical exhaustion. The administration of malic acid to rats has been shown to elevate mitochondrial malate and increase mitochondrial respiration and energy production. Surprisingly, relatively small amounts of exogenous malic acid were required to increase mitochondrial energy production and ATP formation. Under hypoxic conditions there is an increased demand and utilization of malic acid, and this demand is normally met by increasing the synthesis of malic acid through gluconeogenesis and muscle protein
breakdown. This ultimately results in muscle breakdown and damage.
In a study on the effect of the oral administration of malic acid to rats, a significant increase in anaerobic endurance was found. Interestingly, the improvement in endurance was not accompanied by an increase in carbohydrate and oxygen utilization, suggesting that malic acid has carbohydrate and oxygen-sparing effects. In addition, malic acid is the only metabolite of the citric acid cycle positively correlated with physical activity. It has also been demonstrated that exercise-induced mitochondrial respiration is associated with an accumulation of malic acid. In humans, endurance training is associated with a significant increase in the enzymes involved with malic acid metabolism.
Because of the compelling evidence that malic acid plays a central role in energy production, especially during hypoxic conditions, malic acid supplements have been examined for their effects on FM. Subjective improvement in pain was observed within 48 hours of supplementation with 1200 - 2400 milligrams of malic acid, and this improvement was lost following the discontinuation of malic acid for 48 hours. While these studies also used magnesium supplements, due to the fact that magnesium is often low in FM patients, the rapid improvement following malic acid, as well as the rapid deterioration after discontinuation, suggests that malic acid is the most important component. This interesting theory of localized hypoxia in FM, and the ability of malic acid to overcome the block in energy production that this causes, should provide hope for those afflicted with FM. The potential for malic acid supplements, however, reaches much farther than FM. In light of malic acids ability to improve animal exercise performance, its potential for human athletes is particularly exciting.
Additionally, many hypoxia related conditions, such as respiratory and circulatory insufficiency, are associated with deficient energy production. Therefore, malic acid supplements may be of benefit in these conditions. Chronic Fatigue Syndrome has also been found to be associated with FM, and malic acid supplementation may be of use in improving energy production in this condition as well. Lastly, malic acid may be of use as a general supplement aimed at ensuring an optimal level of malic acid within the cells, and thus, maintaining an optimal level of energy production.
Metagenics Fibroplex has: Thiamin (as thiamin mononitrate) 50 mgVitamin B6 (as pyridoxine HCl) 50 mgMagnesium (as magnesium bis-glycinate†) 150 mgManganese (as manganese glycinate†) 5 mgMalic Acid 600 mg
Metagenics Fibroplex® Plus - Support for Muscle Tenderness and Discomfort
Fibroplex® Plus provides targeted nutritional support for soft tissues in those with muscle tenderness and discomfort. Featuring a blend of specific vitamins, minerals, and amino acids in an easy-to-use delivery form, this specialized formula works by supporting cellular energy production and muscular and nervous system function.
Improvement in pain observed within 48 hours of supplementation with 1200-2400 mg. of malic acid per day. Buy Metagenics Fibroplex with magnesium and malic acid at a discount
Combine Bioenergy Corvalen Ribose with Metagenics Fibroplex for muscle pains and energy - Corvalen Lowest Price with Free Shipping
Primary fibromyalgia (FM) is a condition affecting principally middle-aged women, characterized by a syndrome of generalized musculoskeletal pain, aches, stiffness, and tenderness at specific anatomical sites. This condition is considered primary when there are no obvious causes. Since it was first described, FM has become recognized as a fairly common rheumatic complaint with a clinical prevalence of 6 to 20 percent. Additionally, FM has been associated with irritable bowel syndrome, tension headache, mitral valve prolapse, and chronic fatigue syndrome. Numerous treatment modalities have been attempted to treat patients with FM, but unfortunately the results have usually been poor. The primary reason for this lack of success was undoubtedly due to our lack of understanding FMs etiology.
In recent years, evidence has accumulated to suggest that FM is the result of local hypoxia in the muscles. For instance, patients with FM have low muscle-tissue oxygen pressure in affected muscles, and to a lesser degree the same was found in other tissues. Muscle biopsies from affected areas showed muscle tissue breakdown and mitochondrial damage. Additionally, low levels of the high energy phosphates ATP, ADP, and phosphocreatine were found. It has been hypothesized that in hypoxic muscle tissues glycolysis is inhibited, reducing ATP synthesis. This stimulates the process of gluconeogenesis, which results in the breakdown of muscle proteins to amino acids that can be utilized as substrates for ATP synthesis. This muscle tissue breakdown, which has been observed in muscle biopsies taken from FM patients, is hypothesized to result in the muscle pain characteristic of FM.
Malic acid is both derived from food sources and synthesized in the body through the citric acid (Krebs) cycle. Its importance to the production of energy in the body during both aerobic and anaerobic conditions is well established. Under aerobic conditions, the oxidation of malate to oxaloacetate provides reducing equivalents to the mitochondria through the malate-aspartate redox shuttle. During anaerobic conditions, where a buildup of excess of reducing equivalents inhibits glycolysis, malic acids simultaneous reduction to succinate and oxidation to oxaloacetate is capable of removing the accumulating reducing equivalents. This allows malic acid to reverse hypoxias inhibition of glycolysis and energy production. This may allow malic acid to improve energy production in FM, reversing the negative effect of the relative hypoxia that has been found in these patients.
Because of its obvious relationship to energy depletion during exercise, malic acid may be of benefit to healthy individuals interested in maximizing their energy production, as well as those with FM. In the rat it has been found that only tissue malate is depleted following exhaustive physical activity. Other key metabolites from the citric acid cycle needed for energy production were found to be unchanged. Because of this, a deficiency of malic acid has been hypothesized to be a major cause of physical exhaustion. The administration of malic acid to rats has been shown to elevate mitochondrial malate and increase mitochondrial respiration and energy production. Surprisingly, relatively small amounts of exogenous malic acid were required to increase mitochondrial energy production and ATP formation. Under hypoxic conditions there is an increased demand and utilization of malic acid, and this demand is normally met by increasing the synthesis of malic acid through gluconeogenesis and muscle protein
breakdown. This ultimately results in muscle breakdown and damage.
In a study on the effect of the oral administration of malic acid to rats, a significant increase in anaerobic endurance was found. Interestingly, the improvement in endurance was not accompanied by an increase in carbohydrate and oxygen utilization, suggesting that malic acid has carbohydrate and oxygen-sparing effects. In addition, malic acid is the only metabolite of the citric acid cycle positively correlated with physical activity. It has also been demonstrated that exercise-induced mitochondrial respiration is associated with an accumulation of malic acid. In humans, endurance training is associated with a significant increase in the enzymes involved with malic acid metabolism.
Because of the compelling evidence that malic acid plays a central role in energy production, especially during hypoxic conditions, malic acid supplements have been examined for their effects on FM. Subjective improvement in pain was observed within 48 hours of supplementation with 1200 - 2400 milligrams of malic acid, and this improvement was lost following the discontinuation of malic acid for 48 hours. While these studies also used magnesium supplements, due to the fact that magnesium is often low in FM patients, the rapid improvement following malic acid, as well as the rapid deterioration after discontinuation, suggests that malic acid is the most important component. This interesting theory of localized hypoxia in FM, and the ability of malic acid to overcome the block in energy production that this causes, should provide hope for those afflicted with FM. The potential for malic acid supplements, however, reaches much farther than FM. In light of malic acids ability to improve animal exercise performance, its potential for human athletes is particularly exciting.
Additionally, many hypoxia related conditions, such as respiratory and circulatory insufficiency, are associated with deficient energy production. Therefore, malic acid supplements may be of benefit in these conditions. Chronic Fatigue Syndrome has also been found to be associated with FM, and malic acid supplementation may be of use in improving energy production in this condition as well. Lastly, malic acid may be of use as a general supplement aimed at ensuring an optimal level of malic acid within the cells, and thus, maintaining an optimal level of energy production.
Metagenics Fibroplex has: Thiamin (as thiamin mononitrate) 50 mgVitamin B6 (as pyridoxine HCl) 50 mgMagnesium (as magnesium bis-glycinate†) 150 mgManganese (as manganese glycinate†) 5 mgMalic Acid 600 mg
Metagenics Fibroplex® Plus - Support for Muscle Tenderness and Discomfort
Fibroplex® Plus provides targeted nutritional support for soft tissues in those with muscle tenderness and discomfort. Featuring a blend of specific vitamins, minerals, and amino acids in an easy-to-use delivery form, this specialized formula works by supporting cellular energy production and muscular and nervous system function.
- Provides targeted nutrition for soft tissue in those with muscle tenderness and discomfort.
- Provides targeted support for energy metabolism and neuromuscular function.
- Supports cellular energy production and mitochondrial function.
- Provides magnesium in the form of an amino acid chelate designed to be easily absorbed.
Friday, March 21, 2008
Special Report: Condition Specific Nutrition CORvalenM
Buy CorvalenM or Corvalen at the lowest price with FREE Shipping
by John St. Cyr, M.D.
CORvalenM™ is the common denominator for all individuals needing to restore cellular energy. As a product extension of CORvalen, a medical food for heart disease patients, it was created to help those suffering from myalgia and chronic fatigue. However, because of the benefits CORvalenM provided to its users, it was also discovered that active individuals could reap the benefits of this natural supplement.
The Ingredients
A variety of conditions can leave people constantly fatigued, short of breath, stiff and sore, making it impossible to face life’s daily activities. Over exertion of or exercise weaken muscles and drain energy reserves, leaving people tired and achy. Often, this fatigue, shortness of breath, soreness, stiffness, and general lack of well-being are associated with depleted energy from the cells and tissues. CORvalenM, with D-ribose, magnesium and malic acid (three substances found naturally in your body) has been clinically proven to be critical in rebuilding cellular energy. The results are dramatic, with people feeling less pain and more energy. D-ribose, the main ingredient in CORvalenM, is a fivecarbon monosaccharide that is vital for the cellular synthesis of ATP (adenosine triphosphate). ATP is the energy of life, and ribose is the fundamental building block of ATP. Without ribose, the process of energy synthesis slows dramatically. Ribose has been clinically proven to effectively speed energy recovery in cells and to improve cardiac function, muscle recovery, and overall quality of life.
The Benefits
Whether suffering from myalgia or chronic fatigue, or needing to recover faster during endurance training, CORvalenM is the perfect natural supplement. When hard work, strenuous exercise, or certain medical conditions stress cells, cellular energy is burned faster than it can be restored. The result is pain, soreness, stiffness, and fatigue. Healthy cells often can rebuild these energy levels eventually, but the process is slow. And chronically energy-starved cells may never fully recover. CORvalenM accelerates this recovery. From endurance athletes to active people who like to run or take a long walk, high energy levels are important to everyone. But energy is especially critical to people who suffer from debilitating myalgia, soreness, stiffness, and fatigue. By taking CORvalenM, normal energy levels are restored and the whole body feels more energetic. More importantly, people taking CORvalenM report an increased sense of well-being and an improved quality of life. CORvalenM is proven safe, effective and beneficial to those needing to restore energy, minimize fatigue and alleviate muscle pain, soreness and stiffness.
by John St. Cyr, M.D.
CORvalenM™ is the common denominator for all individuals needing to restore cellular energy. As a product extension of CORvalen, a medical food for heart disease patients, it was created to help those suffering from myalgia and chronic fatigue. However, because of the benefits CORvalenM provided to its users, it was also discovered that active individuals could reap the benefits of this natural supplement.
The Ingredients
A variety of conditions can leave people constantly fatigued, short of breath, stiff and sore, making it impossible to face life’s daily activities. Over exertion of or exercise weaken muscles and drain energy reserves, leaving people tired and achy. Often, this fatigue, shortness of breath, soreness, stiffness, and general lack of well-being are associated with depleted energy from the cells and tissues. CORvalenM, with D-ribose, magnesium and malic acid (three substances found naturally in your body) has been clinically proven to be critical in rebuilding cellular energy. The results are dramatic, with people feeling less pain and more energy. D-ribose, the main ingredient in CORvalenM, is a fivecarbon monosaccharide that is vital for the cellular synthesis of ATP (adenosine triphosphate). ATP is the energy of life, and ribose is the fundamental building block of ATP. Without ribose, the process of energy synthesis slows dramatically. Ribose has been clinically proven to effectively speed energy recovery in cells and to improve cardiac function, muscle recovery, and overall quality of life.
The Benefits
Whether suffering from myalgia or chronic fatigue, or needing to recover faster during endurance training, CORvalenM is the perfect natural supplement. When hard work, strenuous exercise, or certain medical conditions stress cells, cellular energy is burned faster than it can be restored. The result is pain, soreness, stiffness, and fatigue. Healthy cells often can rebuild these energy levels eventually, but the process is slow. And chronically energy-starved cells may never fully recover. CORvalenM accelerates this recovery. From endurance athletes to active people who like to run or take a long walk, high energy levels are important to everyone. But energy is especially critical to people who suffer from debilitating myalgia, soreness, stiffness, and fatigue. By taking CORvalenM, normal energy levels are restored and the whole body feels more energetic. More importantly, people taking CORvalenM report an increased sense of well-being and an improved quality of life. CORvalenM is proven safe, effective and beneficial to those needing to restore energy, minimize fatigue and alleviate muscle pain, soreness and stiffness.
Wednesday, November 7, 2007
Fibromyalgia is the result of a mismatch between sensory and motor systems, new research suggests
BATH, England, Oct. 31, 2007 - The unexplained pain experienced by patients with Fibromyalgia is the result of a mismatch between sensory and motor systems, new research suggests.
In a study published in the journal Rheumatology*, researchers asked patients to look at a reflection of one arm whilst moving their other in a different direction which was hidden behind the mirror. This created a mismatch between what the brain sees via sensory input and what it feels through the motor system that controls movement.
Of the 29 patients involved in the study, 26 reported feeling a transient increase in pain, temperature change or heaviness in their hidden limb - all symptoms of a ‘flare up’ of their condition. This suggests that a mismatch between sensory and motor neurons could be at the root of the Fibromyalgia – a condition affecting one in 100 people in the UK at some stage of their lives.
“The chronic pain experienced by people with Fibromyalgia is hard to understand because there are no obvious clinical signs that pain should be experienced,” said Dr. Candy McCabe, one of the researchers involved in the University of Bath and Royal National Hospital for Rheumatic Diseases study. “We have shown that by confusing the motor and sensory systems we can exacerbate the symptoms felt by people diagnosed with the condition. This adds to a growing body of evidence that many of the symptoms of this common disorder may be perpetuated, or even triggered, by this sensory-motor conflict.
“We have had some success to date in using a similar technique to help alleviate the symptoms of this kind of chronic pain. This works by helping the brain to see a limb moving freely without pain – although in reality it is a reflection of their pain-free limb.”
Volunteers in the study were asked to perform a series of bilateral upper and lower limb movements with a mirror in front of them at a right-angle. This meant that one limb was obscured from view behind the mirror whilst they could clearly see the other limb and its reflection. They first carried out the same movements with both limbs, and then made different movements. This enabled the researchers to see [the effect of] confusing what the brain could see with what it could feel.
“Nearly all of the group reported an increase in the sensations connected with their condition in the hidden limb,” said Dr. McCabe, who works in the University's School for Health. “This provides strong evidence that sensory-motor conflict is at the heart of this condition. Some clinicians do not recognize Fibromyalgia as a diagnosis because of a lack of clinical reason for the pain.
“It is often considered to be a reflection of anxiety or attention seeking behavior which, for people with the condition, can be very hard to deal with. Nevertheless, Fibromyalgia is one of the most common conditions seen by rheumatologists. Hopefully we are beginning to understand more about the condition, and taking steps toward how it might be treated in the future.”
People with Fibromyalgia complain of widespread pain, multiple tender points, stiffness, sleep disturbance and fatigue. Around nine out of ten of those affected by Fibromyalgia are women. In most cases it develops between the ages of 30 and 60, but it can develop in people of any age, including children and the elderly. There are around 14,700 new cases in the UK each year.
Note: The Royal National Hospital for Rheumatic Diseases NHS Foundation Trust…[home of a Specialist CFS/ME Service for Children and Young Adults] is a national specialist rehabilitation and rheumatology hospital based in Bath. Offering services to adults, children and young people, the trust has expertise general and complex: rheumatological and musculoskeletal conditions, neurological rehabilitation, pain management, management programs for people who suffer from chronic pain and Chronic Fatigue Syndrome / ME.
___* This press release refers to the article “Somaesthetic disturbances in Fibromyalgia are exaggerated by sensory-motor conflict: Implications for chronicity of the disease,” published in the October issue of the journal Rheumatology.
You can find a summary abstract of the article at http://www.immunesupport.com/library/showarticle.cfm/id/8347 and the full text is available free at http://rheumatology.oxfordjournals.org/cgi/reprint/46/10/1587
In a study published in the journal Rheumatology*, researchers asked patients to look at a reflection of one arm whilst moving their other in a different direction which was hidden behind the mirror. This created a mismatch between what the brain sees via sensory input and what it feels through the motor system that controls movement.
Of the 29 patients involved in the study, 26 reported feeling a transient increase in pain, temperature change or heaviness in their hidden limb - all symptoms of a ‘flare up’ of their condition. This suggests that a mismatch between sensory and motor neurons could be at the root of the Fibromyalgia – a condition affecting one in 100 people in the UK at some stage of their lives.
“The chronic pain experienced by people with Fibromyalgia is hard to understand because there are no obvious clinical signs that pain should be experienced,” said Dr. Candy McCabe, one of the researchers involved in the University of Bath and Royal National Hospital for Rheumatic Diseases study. “We have shown that by confusing the motor and sensory systems we can exacerbate the symptoms felt by people diagnosed with the condition. This adds to a growing body of evidence that many of the symptoms of this common disorder may be perpetuated, or even triggered, by this sensory-motor conflict.
“We have had some success to date in using a similar technique to help alleviate the symptoms of this kind of chronic pain. This works by helping the brain to see a limb moving freely without pain – although in reality it is a reflection of their pain-free limb.”
Volunteers in the study were asked to perform a series of bilateral upper and lower limb movements with a mirror in front of them at a right-angle. This meant that one limb was obscured from view behind the mirror whilst they could clearly see the other limb and its reflection. They first carried out the same movements with both limbs, and then made different movements. This enabled the researchers to see [the effect of] confusing what the brain could see with what it could feel.
“Nearly all of the group reported an increase in the sensations connected with their condition in the hidden limb,” said Dr. McCabe, who works in the University's School for Health. “This provides strong evidence that sensory-motor conflict is at the heart of this condition. Some clinicians do not recognize Fibromyalgia as a diagnosis because of a lack of clinical reason for the pain.
“It is often considered to be a reflection of anxiety or attention seeking behavior which, for people with the condition, can be very hard to deal with. Nevertheless, Fibromyalgia is one of the most common conditions seen by rheumatologists. Hopefully we are beginning to understand more about the condition, and taking steps toward how it might be treated in the future.”
People with Fibromyalgia complain of widespread pain, multiple tender points, stiffness, sleep disturbance and fatigue. Around nine out of ten of those affected by Fibromyalgia are women. In most cases it develops between the ages of 30 and 60, but it can develop in people of any age, including children and the elderly. There are around 14,700 new cases in the UK each year.
Note: The Royal National Hospital for Rheumatic Diseases NHS Foundation Trust…[home of a Specialist CFS/ME Service for Children and Young Adults] is a national specialist rehabilitation and rheumatology hospital based in Bath. Offering services to adults, children and young people, the trust has expertise general and complex: rheumatological and musculoskeletal conditions, neurological rehabilitation, pain management, management programs for people who suffer from chronic pain and Chronic Fatigue Syndrome / ME.
___* This press release refers to the article “Somaesthetic disturbances in Fibromyalgia are exaggerated by sensory-motor conflict: Implications for chronicity of the disease,” published in the October issue of the journal Rheumatology.
You can find a summary abstract of the article at http://www.immunesupport.com/library/showarticle.cfm/id/8347 and the full text is available free at http://rheumatology.oxfordjournals.org/cgi/reprint/46/10/1587
Wednesday, September 19, 2007
Virus Identified in 82% of ME/CFS Patients
Virus Identified in 82% of ME/CFS Patients
by Rich Carson
ImmuneSupport.com - 09-18-2007
I was delighted to see the new research suggesting a possible viral cause in a significant subset of ME/CFS patients.
The big news is that 82% of 165 patients had evidence of chronic enterovirus infection using gastric (stomach) biopsy, compared with only 20% of non-patients. The research, with its statistically significant numbers, was impressive enough to be published in the September issue of the respected Journal of Clinical Pathology.
Enteroviruses are the second most common viral infection in humans next to the common cold, and two notable enteroviruses are polio virus and Coxsackievirus. Infection usually causes asymptomatic gastric and respiratory infection, and the virus has previously been isolated from ME/CFS brain, muscle, and heart tissue.
It is too early to jump on the cause and effect bandwagon, and I am sure many of you remember earlier “breakthroughs” including EBV, CMV, retrovirus, stealth virus, spuma virus, HHV-6 and HHV-7. Nevertheless, it was determined that the virus was causing a chronic, inflammatory condition in the study participants, and it is pretty hard not to be impressed with a positive rate of 82%. Could we finally have a smoking gun?
I do not mean to suggest that the viruses above do not play at least some role in many cases of ME/CFS. In fact I am convinced that HHV-6A plays a major part in a good percentage of cases of ME/CFS. Please visit the website of the respected Human Herpesvirus-6 (HHV-6) Foundation for compelling evidence - http://www.hhv-6foundation.org/
The take away? Patients will have a reason for hope if it is determined that this enterovirus is indeed a cause of ME/CFS. I find this research impressive and worthy of optimism. ProHealth will keep you informed as the research unfolds.
by Rich Carson
ImmuneSupport.com - 09-18-2007
I was delighted to see the new research suggesting a possible viral cause in a significant subset of ME/CFS patients.
The big news is that 82% of 165 patients had evidence of chronic enterovirus infection using gastric (stomach) biopsy, compared with only 20% of non-patients. The research, with its statistically significant numbers, was impressive enough to be published in the September issue of the respected Journal of Clinical Pathology.
Enteroviruses are the second most common viral infection in humans next to the common cold, and two notable enteroviruses are polio virus and Coxsackievirus. Infection usually causes asymptomatic gastric and respiratory infection, and the virus has previously been isolated from ME/CFS brain, muscle, and heart tissue.
It is too early to jump on the cause and effect bandwagon, and I am sure many of you remember earlier “breakthroughs” including EBV, CMV, retrovirus, stealth virus, spuma virus, HHV-6 and HHV-7. Nevertheless, it was determined that the virus was causing a chronic, inflammatory condition in the study participants, and it is pretty hard not to be impressed with a positive rate of 82%. Could we finally have a smoking gun?
I do not mean to suggest that the viruses above do not play at least some role in many cases of ME/CFS. In fact I am convinced that HHV-6A plays a major part in a good percentage of cases of ME/CFS. Please visit the website of the respected Human Herpesvirus-6 (HHV-6) Foundation for compelling evidence - http://www.hhv-6foundation.org/
The take away? Patients will have a reason for hope if it is determined that this enterovirus is indeed a cause of ME/CFS. I find this research impressive and worthy of optimism. ProHealth will keep you informed as the research unfolds.
Friday, August 31, 2007
Ribose (Corvalen)-An Exciting New Discovery!
Corvalen (D-Ribose by Valen Labs) is an outstanding new nutrient (a special sugar-even OK for those who need to avoid sugar!) for those of you who want a powerful energy boost! In addition to its role in making DNA and RNA, those of you familiar with biochemistry remember Ribose as the key building block for making energy. In fact, the main energy molecules (like “Energy dollars”) in your body (ATP, FADH, etc.) are made of ribose plus B vitamins/phosphate. That makes these energy molecules similar to the paper that money is printed on- kind of like being able to print your own energy currency!
Corvalen has many uses, including treating heart muscle weakness (Congestive Heart Failure). We were so impressed with this product that our research center recently completed a study(to be published Nov 2006) reported on in the national news services. Two thirds of CFS/Fibromyalgia patients improved, with an average increase in quality of life of ~25%- outstanding for a single nutrient!
Take 1 scoop 3 times a day for 2 weeks, then decrease to a scoop twice a day, but lower the dose or take it with food if you get hyper from being too energized. The use of Ribose (Corvalen) is a major step forward in treating fatigue with the average CFS/FMS patient in the study having a 45% improvement in energy after 2-3 weeks. In our study, pain, sleep, and “brain fog’ also improved.
by Jacob Teitelbaum M.D.
Buy CorvalenM and Corvalen at a discount with free shipping.
Corvalen has many uses, including treating heart muscle weakness (Congestive Heart Failure). We were so impressed with this product that our research center recently completed a study(to be published Nov 2006) reported on in the national news services. Two thirds of CFS/Fibromyalgia patients improved, with an average increase in quality of life of ~25%- outstanding for a single nutrient!
Take 1 scoop 3 times a day for 2 weeks, then decrease to a scoop twice a day, but lower the dose or take it with food if you get hyper from being too energized. The use of Ribose (Corvalen) is a major step forward in treating fatigue with the average CFS/FMS patient in the study having a 45% improvement in energy after 2-3 weeks. In our study, pain, sleep, and “brain fog’ also improved.
by Jacob Teitelbaum M.D.
Buy CorvalenM and Corvalen at a discount with free shipping.
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