Low-dose Exposures
Two decades of research indicate that very low-dose exposures to toxic chemicals can have profound health effects. This counters the long-held belief that “the dose makes the poison” – a rationale that underlies much chemical regulation, including the use of various chemicals in cosmetics (i). The inaccurate assumption that very small amounts of toxic chemicals are safe allows for the continued use of toxic chemicals in personal care products (ii). Buy only natural, organic, non-toxic products.
There are at least three key problems with this assumption. First, this assumes that low doses are truly safe, which may not be the case. Research on laboratory animals, cell cultures and wildlife suggests that in some cases low-dose exposures may have more profound effects than higher exposures (iii). Second, this assumption of safety at low doses overlooks the fact that many of the toxic chemicals that appear in cosmetics and personal care products tend to show up in several products an average person uses daily, and that many of these chemicals show up in other consumer products as well (iv). As a result, what seem like small exposures add up to larger doses.
Finally, a long-standing approach to chemical regulation looks at chemicals one at a time. However, daily life exposes individuals to a multitude of various ingredients. For instance, an Environmental Working Group report shows that women use 12 cosmetic products with 168 unique ingredients each day and men use 6 products with an average of 85 ingredients (v). These ingredients, in combination with exposures from other consumer products and pollutants in the air and water, add up to a phenomenal array of combined exposures, in effect adding up to hundreds of exposures every day (vi).
Research indicates that, in many cases, these exposures add up and work in combination to affect health in ways that may be more profound than single exposures. Taking in multiple chemicals can have an additive effect, whereby multiple small exposures add up to a lot (2+3=5), or a synergistic effect, whereby multiple exposures increase the toxic effects of one another (2+3=10) (vii). For instance, several studies have found that combinations of various chemicals with estrogenic properties may have additive (viii) or synergistic effects (ix).
In addition, the timing of exposure may moderate the effects of low doses, so that low doses at certain points in development – prenatally, during puberty, etc. – may have stronger or qualitatively different effects on health (x).
More Information
For more information about how small doses of chemicals impact our long-term health, visit The Endocrine Disruption Exchange.
i Gray, J (2008). State of the Evidence: The Connection between Breast Cancer and the Environment. San Francisco, CA: Breast Cancer Fund.
ii Environmental Working Group (2004). Exposures Add Up – Survey Results. Available online http://www.cosmeticsdatabase.com/research/exposures/php. Accessed August 19, 2008.
iii Gray, J (2008). State of the Evidence: The Connection between Breast Cancer and the Environment. San Francisco, CA: Breast Cancer Fund.
iv Environmental Working Group (2004). Exposures Add Up – Survey Results. Available online http://www.cosmeticsdatabase.com/research/exposures/php. Accessed August 19, 2008.
v Environmental Working Group (2004). Exposures Add Up – Survey Results. Available online http://www.cosmeticsdatabase.com/research/exposures/php. Accessed August 19, 2008.
vi Centers for Disease Control and Prevention (CDC) (2003). Second National Report on Human Exposure to Environmental Chemicals. Available online at http://www.cdc.gov/exposurereport/. Accessed August 19, 2008.
vii Gray, J (2008). State of the Evidence: The Connection between Breast Cancer and the Environment. San Francisco, CA: Breast Cancer Fund.
viii Ramamoorthy K, Wang F, Chen IC, Safe S, Norris JD, McDonnell DP, Gaido KW, Bocchinfuso WP, Korach KS (1997). Potency of combined estrogenic pesticides. Science 275: 405-6.
Foster WG, Younglai EV, Boutross- Tadross O, Hughes CL, Wade MG (2004). Mammary gland morphology in Sprague-Dawley rats following treatment with an organochlorine mixture in utero and neonatal genistein. Toxicological Sciences 77: 91-100.
ix Xie L, Thrippleton K, Irwin MA, Siemering GS, Mekebri A, Crane D, Berry K, Schlenk D (2005). Evaluation of estrogenic activities of aquatic herbicides and surfactants using a rainbow trout vitellogenin assay. Toxicological Sciences 77: 91-100.
Kortenkamp A (2006). Breast cancer, oestrogens and environmental pollutants: a re-evaluation from a mixture perspective. International Journal of Andrology 29: 193-198.
x Gray, J (2008). State of the Evidence: The Connection between Breast Cancer and the Environment. San Francisco, CA: Breast Cancer Fund.
Showing posts with label Parabens. Show all posts
Showing posts with label Parabens. Show all posts
Monday, May 24, 2010
Measuring the Pollution in People
Toxic chemicals in personal care products have been proven to have an accumulative affect in our bodies. For those with chronic illnesses, that burden becomes even greater. It is so important to avoid toxic chemicals as much as possible and lighten the load. Buy only natural, organic non-toxic products.
Measuring the Pollution in People
A number of striking studies (i) have shown that the man-made chemicals in our environment and in consumer products—including cosmetics—make their way into our bodies. Many of the chemicals found in cosmetics are absorbed by the skin into the body, and can be detected in blood or urine.
The length of time chemicals remain in the body varies from chemical to chemical and ranges from hours to decades. For chemicals that are excreted quickly, the fact that we can so consistently measure them indicates continual exposures that may have long-term effects on health.
Body Burden and Biomonitoring
Body burden refers to the levels of man-made chemicals in an individual’s body, generally measured through blood or urine. Large-scale biomonitoring programs that assess the levels of chemicals in a population or subset of a population would greatly support the ability of researchers to explore the links between exposures and disease. A gap in determining the long-term effects of chemical exposures upon disease has long been a lack of knowledge about chemical exposures and the intake of environmental toxins into the body. Ongoing biomonitoring programs would fill this vital data gap.
The Pollution in People
The largest U.S. body burden study to date measured the levels of 148 chemicals in approximately 3,000 people of varying ages, ethnicities and geographical locations (ii). This study, by the U.S. Centers for Disease Control, detected a common sunscreen ingredient, benzophenone-3 (BP-3) in 96.8 percent of individuals (iii), and triclosan, an antibacterial agent often used in antibacterial soaps, in 74.6 percent of individuals (iv). A CDC study found residues of four different phthalates in more than 75 percent of subjects (v). Phthalates are found in numerous cosmetics, often as a constituent ingredient of fragrances. A 2008 study of teen girls by the Environmental Working Group revealed 16 hormone-altering cosmetics chemicals in their young test subjects (vi).
The CDC tests of 148 chemicals represents a very small percentage of the over 80,000 chemicals manufactured and the approximately 10,000 chemicals used in cosmetic products. The next edition of the CDC report, anticipated in 2009, will include measurements of 250 chemicals, an increase that still doesn't approach the total number of chemicals in commerce. Nevertheless, this and other studies illustrate that chemicals we use in an array of consumer products make their way into our bodies (vii). This knowledge also furthers our understanding of the links between the chemicals we use, the absorption of these chemicals into our bodies, and the known and probable health effects of these chemicals.
i.Commonweal Biomonitoring Resource Center (2005). Taking It All In: Documenting Chemical Pollution in Californians through Biomonitoring. Available online at http://www.commonweal.org/programs/download/TIAI_1205.pdf. Accessed August 19, 2008.
Environmental Working Group (2006). Across Generations: Industrial Chemicals in Mothers and Daughters: The pollution we share and inherit. Available online at http://www.ewg.org/reports/generations/. Accessed August 19, 2008.
Environmental Working Group (2005). Body Burden: The Pollution in Newborns. Available online at: http://www.ewg.org/node/17686. Accessed August 19, 2008.
Environmental Working Group (2003). Body Burden: The Pollution in People. Available online at: http://archive.ewg.org/reports/bodyburden1/. Accessed August 19, 2008.
ii Centers for Disease Control and Prevention (CDC) (2005). Third National Report on Human Exposure to Environmental Chemicals. Available online at http://www.cdc.gov/exposurereport/. Accessed December 23, 2008.
iii Calafat AM, Wong LY, Ye X, Reidy JA, Needham LL. Concentrations of the Sunscreen Agent, Benzophenone-3, in Residents of the United States: National Health and Nutrition Examination Survey 2003-2004. Environ Health Perspect 116:893–897 (2008).
iv Calafat AM, Ye X, Wong LY, Reidy JA, Needham LL. Urinary Concentrations of Triclosan in the U.S. Population: 2003–2004. Environmental Health Perspectives, 116:303–307 (2008).
v Silva MJ, Barr DB, Reidy JA, Malek NA, Hodge CC, Caudill SP, Brock JW, Needham LL, Calafat AM. “Urinary Levels of Seven Phthalate Metabolites in the U.S. Population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000,” Environmental Health Perspectives, 112(3): 331-338 (2004).
vi Sutton, R (2008). Teen Girls' Body Burden of Hormone-Altering Cosmetics Chemicals. Available online at http://www.ewg.org/reports/teens. Accessed October 10, 2008.
vii Commonweal and Breast Cancer Fund (2005). Taking It All In: Documenting Chemical Pollution in Californians through Biomonitoring. Available online at http://www.commonweal.org/programs/download/TIAI_1205.pdf. Accessed August 19, 2008.
Environmental Working Group (2006). Across Generations: Industrial Chemicals in Mothers and Daughters: The pollution we share and inherit. Available online at http://www.ewg.org/reports/generations/. Accessed August 19, 2008.
Environmental Working Group (2005). Body Burden: The Pollution in Newborns. Available online at: http://www.ewg.org/node/17686. Accessed August 19, 2008.
Environmental Working Group (2003). Body Burden: The Pollution in People. Available online at: http://archive.ewg.org/reports/bodyburden1/. Accessed August 19, 2008.
Measuring the Pollution in People
A number of striking studies (i) have shown that the man-made chemicals in our environment and in consumer products—including cosmetics—make their way into our bodies. Many of the chemicals found in cosmetics are absorbed by the skin into the body, and can be detected in blood or urine.
The length of time chemicals remain in the body varies from chemical to chemical and ranges from hours to decades. For chemicals that are excreted quickly, the fact that we can so consistently measure them indicates continual exposures that may have long-term effects on health.
Body Burden and Biomonitoring
Body burden refers to the levels of man-made chemicals in an individual’s body, generally measured through blood or urine. Large-scale biomonitoring programs that assess the levels of chemicals in a population or subset of a population would greatly support the ability of researchers to explore the links between exposures and disease. A gap in determining the long-term effects of chemical exposures upon disease has long been a lack of knowledge about chemical exposures and the intake of environmental toxins into the body. Ongoing biomonitoring programs would fill this vital data gap.
The Pollution in People
The largest U.S. body burden study to date measured the levels of 148 chemicals in approximately 3,000 people of varying ages, ethnicities and geographical locations (ii). This study, by the U.S. Centers for Disease Control, detected a common sunscreen ingredient, benzophenone-3 (BP-3) in 96.8 percent of individuals (iii), and triclosan, an antibacterial agent often used in antibacterial soaps, in 74.6 percent of individuals (iv). A CDC study found residues of four different phthalates in more than 75 percent of subjects (v). Phthalates are found in numerous cosmetics, often as a constituent ingredient of fragrances. A 2008 study of teen girls by the Environmental Working Group revealed 16 hormone-altering cosmetics chemicals in their young test subjects (vi).
The CDC tests of 148 chemicals represents a very small percentage of the over 80,000 chemicals manufactured and the approximately 10,000 chemicals used in cosmetic products. The next edition of the CDC report, anticipated in 2009, will include measurements of 250 chemicals, an increase that still doesn't approach the total number of chemicals in commerce. Nevertheless, this and other studies illustrate that chemicals we use in an array of consumer products make their way into our bodies (vii). This knowledge also furthers our understanding of the links between the chemicals we use, the absorption of these chemicals into our bodies, and the known and probable health effects of these chemicals.
i.Commonweal Biomonitoring Resource Center (2005). Taking It All In: Documenting Chemical Pollution in Californians through Biomonitoring. Available online at http://www.commonweal.org/programs/download/TIAI_1205.pdf. Accessed August 19, 2008.
Environmental Working Group (2006). Across Generations: Industrial Chemicals in Mothers and Daughters: The pollution we share and inherit. Available online at http://www.ewg.org/reports/generations/. Accessed August 19, 2008.
Environmental Working Group (2005). Body Burden: The Pollution in Newborns. Available online at: http://www.ewg.org/node/17686. Accessed August 19, 2008.
Environmental Working Group (2003). Body Burden: The Pollution in People. Available online at: http://archive.ewg.org/reports/bodyburden1/. Accessed August 19, 2008.
ii Centers for Disease Control and Prevention (CDC) (2005). Third National Report on Human Exposure to Environmental Chemicals. Available online at http://www.cdc.gov/exposurereport/. Accessed December 23, 2008.
iii Calafat AM, Wong LY, Ye X, Reidy JA, Needham LL. Concentrations of the Sunscreen Agent, Benzophenone-3, in Residents of the United States: National Health and Nutrition Examination Survey 2003-2004. Environ Health Perspect 116:893–897 (2008).
iv Calafat AM, Ye X, Wong LY, Reidy JA, Needham LL. Urinary Concentrations of Triclosan in the U.S. Population: 2003–2004. Environmental Health Perspectives, 116:303–307 (2008).
v Silva MJ, Barr DB, Reidy JA, Malek NA, Hodge CC, Caudill SP, Brock JW, Needham LL, Calafat AM. “Urinary Levels of Seven Phthalate Metabolites in the U.S. Population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000,” Environmental Health Perspectives, 112(3): 331-338 (2004).
vi Sutton, R (2008). Teen Girls' Body Burden of Hormone-Altering Cosmetics Chemicals. Available online at http://www.ewg.org/reports/teens. Accessed October 10, 2008.
vii Commonweal and Breast Cancer Fund (2005). Taking It All In: Documenting Chemical Pollution in Californians through Biomonitoring. Available online at http://www.commonweal.org/programs/download/TIAI_1205.pdf. Accessed August 19, 2008.
Environmental Working Group (2006). Across Generations: Industrial Chemicals in Mothers and Daughters: The pollution we share and inherit. Available online at http://www.ewg.org/reports/generations/. Accessed August 19, 2008.
Environmental Working Group (2005). Body Burden: The Pollution in Newborns. Available online at: http://www.ewg.org/node/17686. Accessed August 19, 2008.
Environmental Working Group (2003). Body Burden: The Pollution in People. Available online at: http://archive.ewg.org/reports/bodyburden1/. Accessed August 19, 2008.
Tuesday, September 25, 2007
The Hidden Danger in Lotions and Sunscreens & A Natural Sunscreen
Many consumers have long known their favorite lotions and sunscreens contained parabens, or synthetic chemicals used as preservatives. But with more and more products being touted as “paraben-free," many are now wondering, "What, exactly, are parabens, and are they dangerous?"
Parabens, which inhibit the growth of bacteria, yeast, and molds, have been used in personal-care products like shampoos, conditioners, deodorants, and sunscreens for years, allowing these products to survive for months, or years, during shipping and on store shelves.
Studies have now shown that parabens mimic the activity of the hormone estrogen, which is associated with certain forms of breast cancer.
Posted by Dr. Mercola, September 25 2007
Emu Oil is a natural sunscreen that has been used for hundreds of years. See product store for more information.
Parabens, which inhibit the growth of bacteria, yeast, and molds, have been used in personal-care products like shampoos, conditioners, deodorants, and sunscreens for years, allowing these products to survive for months, or years, during shipping and on store shelves.
Studies have now shown that parabens mimic the activity of the hormone estrogen, which is associated with certain forms of breast cancer.
Posted by Dr. Mercola, September 25 2007
Emu Oil is a natural sunscreen that has been used for hundreds of years. See product store for more information.
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